产品货号：
Z20100
中文名称：
MCM2抗体
英文名称：
Anti-MCM2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MCM2 Antibody |
| 指标别名 | BM28;CCNL1;cdc19;CDCL1;D3S3194;KIAA0030;MCM2;MITOTIN;Nuclear protein BM28 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | MCM2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of mouse MCM2(884-904aa DLFKFNKFSRDLKRKLILQQF),different from the related rat sequence by one amino acid. |
| 实际分子量 | 125KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MCM2(MINICHROMOSOME MAINTENANCE,S.CEREVISIAE,HOMOLOG OF,2),also known as MITOTIN,CDCL1 or BM28,is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle,namely,onset of DNA replication and cell division.And it is similar to members of the family of early S-phase proteins.The MCM2 gene is mapped to 3q21.3.The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex(pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.In the G0 stage,the MCM2 and MCM5 proteins were much less abundant than the MCM7 and MCM3 proteins,which suggests that the MCM proteins are not present in stoichiometric amounts and that only a proportion of these molecules actively participate in cell cycle regulation as part of MCM complexes. |
| Uniprot ID | P97310 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | minichromosome maintenance complex component 2 |
| 蛋白名全称 | DNA replication licensing factor MCM2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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